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Using pseudoalignment and base quality to accurately quantify microbial community composition
Pooled DNA from multiple unknown organisms arises in a variety of contexts, for example microbial samples from ecological or human health research. Determining the composition of pooled samples can be difficult, especially at the scale of modern sequencing data and reference databases. Here we propo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945057/ https://www.ncbi.nlm.nih.gov/pubmed/29659582 http://dx.doi.org/10.1371/journal.pcbi.1006096 |