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A comparison of the effects of Methylprednisolone Acetate, Sodium Hyaluronate and Tenoxicam in the treatment of non-reducing disc displacement of the temporomandibular joint
BACKGROUND: This clinical study aimed to radiologically and clinically compare the effect of intra-articular injection of methylprednisolone, sodium hyaluronate or tenoxicam following arthrocentesis with that of arthrocentesis alone in patients with non-reducing disc displacement. MATERIAL AND METHO...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945235/ https://www.ncbi.nlm.nih.gov/pubmed/29680845 http://dx.doi.org/10.4317/medoral.22237 |
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author | Yapıcı-Yavuz, Günay Şimşek-Kaya, Göksel Oğul, Hayri |
author_facet | Yapıcı-Yavuz, Günay Şimşek-Kaya, Göksel Oğul, Hayri |
author_sort | Yapıcı-Yavuz, Günay |
collection | PubMed |
description | BACKGROUND: This clinical study aimed to radiologically and clinically compare the effect of intra-articular injection of methylprednisolone, sodium hyaluronate or tenoxicam following arthrocentesis with that of arthrocentesis alone in patients with non-reducing disc displacement. MATERIAL AND METHODS: A total of 44 patients radiographically diagnosed with non-reducing disc displacement of the temporomandibular joint (TMJ) were randomly divided into four treatment groups, as follows: Group 1, arthrocentesis alone; Group 2, arthrocentesis plus methylprednisolone acetate; Group 3, arthrocentesis plus sodium hyaluronate; Group 4, arthrocentesis plus tenoxicam. Maximum mouth opening (MMO), lateral movement, pain severity and tenderness of TMJ and muscles of mastication on palpation were measured before treatment and at 1 week and 1, 3 and 6 months after treatment. Disc position, presence or absence of disc reduction, level of effusion, joint movement and joint space were also evaluated using magnetic resonance imaging (MRI) before treatment and 6 months after treatment. RESULTS: No significant differences in treatment success were found among the four groups. MRI findings did not vary significantly among the groups, but pre- and post-operative MRI findings varied significantly within all four groups (p<0.001). CONCLUSIONS: According to the data from this study, it may be concluded that either arthrocentesis alone or arthrocentesis with methylprednisolone acetate or sodium hyaluronate or tenoxicam intra-articular injections are similarly effective and promising methods in the treatment of TMJ with non-reducing disc displacement. Key words:Non-reduction disc displacement, arthrocentesis, methylprednisolone, sodium hyaluronate, tenoxicam. |
format | Online Article Text |
id | pubmed-5945235 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-59452352018-05-15 A comparison of the effects of Methylprednisolone Acetate, Sodium Hyaluronate and Tenoxicam in the treatment of non-reducing disc displacement of the temporomandibular joint Yapıcı-Yavuz, Günay Şimşek-Kaya, Göksel Oğul, Hayri Med Oral Patol Oral Cir Bucal Research BACKGROUND: This clinical study aimed to radiologically and clinically compare the effect of intra-articular injection of methylprednisolone, sodium hyaluronate or tenoxicam following arthrocentesis with that of arthrocentesis alone in patients with non-reducing disc displacement. MATERIAL AND METHODS: A total of 44 patients radiographically diagnosed with non-reducing disc displacement of the temporomandibular joint (TMJ) were randomly divided into four treatment groups, as follows: Group 1, arthrocentesis alone; Group 2, arthrocentesis plus methylprednisolone acetate; Group 3, arthrocentesis plus sodium hyaluronate; Group 4, arthrocentesis plus tenoxicam. Maximum mouth opening (MMO), lateral movement, pain severity and tenderness of TMJ and muscles of mastication on palpation were measured before treatment and at 1 week and 1, 3 and 6 months after treatment. Disc position, presence or absence of disc reduction, level of effusion, joint movement and joint space were also evaluated using magnetic resonance imaging (MRI) before treatment and 6 months after treatment. RESULTS: No significant differences in treatment success were found among the four groups. MRI findings did not vary significantly among the groups, but pre- and post-operative MRI findings varied significantly within all four groups (p<0.001). CONCLUSIONS: According to the data from this study, it may be concluded that either arthrocentesis alone or arthrocentesis with methylprednisolone acetate or sodium hyaluronate or tenoxicam intra-articular injections are similarly effective and promising methods in the treatment of TMJ with non-reducing disc displacement. Key words:Non-reduction disc displacement, arthrocentesis, methylprednisolone, sodium hyaluronate, tenoxicam. Medicina Oral S.L. 2018-05 2018-04-24 /pmc/articles/PMC5945235/ /pubmed/29680845 http://dx.doi.org/10.4317/medoral.22237 Text en Copyright: © 2018 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Yapıcı-Yavuz, Günay Şimşek-Kaya, Göksel Oğul, Hayri A comparison of the effects of Methylprednisolone Acetate, Sodium Hyaluronate and Tenoxicam in the treatment of non-reducing disc displacement of the temporomandibular joint |
title | A comparison of the effects of Methylprednisolone Acetate, Sodium
Hyaluronate and Tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
title_full | A comparison of the effects of Methylprednisolone Acetate, Sodium
Hyaluronate and Tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
title_fullStr | A comparison of the effects of Methylprednisolone Acetate, Sodium
Hyaluronate and Tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
title_full_unstemmed | A comparison of the effects of Methylprednisolone Acetate, Sodium
Hyaluronate and Tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
title_short | A comparison of the effects of Methylprednisolone Acetate, Sodium
Hyaluronate and Tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
title_sort | comparison of the effects of methylprednisolone acetate, sodium
hyaluronate and tenoxicam in the treatment of non-reducing disc
displacement of the temporomandibular joint |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945235/ https://www.ncbi.nlm.nih.gov/pubmed/29680845 http://dx.doi.org/10.4317/medoral.22237 |
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