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Microtubule assembly governed by tubulin allosteric gain in flexibility and lattice induced fit
Microtubules (MTs) are key components of the cytoskeleton and play a central role in cell division and development. MT assembly is known to be associated with a structural change in [Formula: see text]-tubulin dimers from kinked to straight conformations. How GTP binding renders individual dimers po...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945277/ https://www.ncbi.nlm.nih.gov/pubmed/29652248 http://dx.doi.org/10.7554/eLife.34353 |