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Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior

Drawing on psychological and sociological theories of crime causation, we tested the hypothesis that genetic risk for low educational attainment (assessed via a genome-wide polygenic score) is associated with criminal offending. We further tested hypotheses of how polygenic risk relates to the devel...

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Autores principales: Wertz, J., Caspi, A., Belsky, D. W., Beckley, A. L., Arseneault, L., Barnes, J. C., Corcoran, D. L., Hogan, S., Houts, R. M., Morgan, N., Odgers, C. L., Prinz, J. A., Sugden, K., Williams, B. S., Poulton, R., Moffitt, T. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945301/
https://www.ncbi.nlm.nih.gov/pubmed/29513605
http://dx.doi.org/10.1177/0956797617744542
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author Wertz, J.
Caspi, A.
Belsky, D. W.
Beckley, A. L.
Arseneault, L.
Barnes, J. C.
Corcoran, D. L.
Hogan, S.
Houts, R. M.
Morgan, N.
Odgers, C. L.
Prinz, J. A.
Sugden, K.
Williams, B. S.
Poulton, R.
Moffitt, T. E.
author_facet Wertz, J.
Caspi, A.
Belsky, D. W.
Beckley, A. L.
Arseneault, L.
Barnes, J. C.
Corcoran, D. L.
Hogan, S.
Houts, R. M.
Morgan, N.
Odgers, C. L.
Prinz, J. A.
Sugden, K.
Williams, B. S.
Poulton, R.
Moffitt, T. E.
author_sort Wertz, J.
collection PubMed
description Drawing on psychological and sociological theories of crime causation, we tested the hypothesis that genetic risk for low educational attainment (assessed via a genome-wide polygenic score) is associated with criminal offending. We further tested hypotheses of how polygenic risk relates to the development of antisocial behavior from childhood through adulthood. Across the Dunedin and Environmental Risk (E-Risk) birth cohorts of individuals growing up 20 years and 20,000 kilometers apart, education polygenic scores predicted risk of a criminal record with modest effects. Polygenic risk manifested during primary schooling in lower cognitive abilities, lower self-control, academic difficulties, and truancy, and it was associated with a life-course-persistent pattern of antisocial behavior that onsets in childhood and persists into adulthood. Crime is central in the nature-nurture debate, and findings reported here demonstrate how molecular-genetic discoveries can be incorporated into established theories of antisocial behavior. They also suggest that improving school experiences might prevent genetic influences on crime from unfolding.
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spelling pubmed-59453012019-03-07 Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior Wertz, J. Caspi, A. Belsky, D. W. Beckley, A. L. Arseneault, L. Barnes, J. C. Corcoran, D. L. Hogan, S. Houts, R. M. Morgan, N. Odgers, C. L. Prinz, J. A. Sugden, K. Williams, B. S. Poulton, R. Moffitt, T. E. Psychol Sci Research Articles Drawing on psychological and sociological theories of crime causation, we tested the hypothesis that genetic risk for low educational attainment (assessed via a genome-wide polygenic score) is associated with criminal offending. We further tested hypotheses of how polygenic risk relates to the development of antisocial behavior from childhood through adulthood. Across the Dunedin and Environmental Risk (E-Risk) birth cohorts of individuals growing up 20 years and 20,000 kilometers apart, education polygenic scores predicted risk of a criminal record with modest effects. Polygenic risk manifested during primary schooling in lower cognitive abilities, lower self-control, academic difficulties, and truancy, and it was associated with a life-course-persistent pattern of antisocial behavior that onsets in childhood and persists into adulthood. Crime is central in the nature-nurture debate, and findings reported here demonstrate how molecular-genetic discoveries can be incorporated into established theories of antisocial behavior. They also suggest that improving school experiences might prevent genetic influences on crime from unfolding. SAGE Publications 2018-03-07 2018-05 /pmc/articles/PMC5945301/ /pubmed/29513605 http://dx.doi.org/10.1177/0956797617744542 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Research Articles
Wertz, J.
Caspi, A.
Belsky, D. W.
Beckley, A. L.
Arseneault, L.
Barnes, J. C.
Corcoran, D. L.
Hogan, S.
Houts, R. M.
Morgan, N.
Odgers, C. L.
Prinz, J. A.
Sugden, K.
Williams, B. S.
Poulton, R.
Moffitt, T. E.
Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title_full Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title_fullStr Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title_full_unstemmed Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title_short Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior
title_sort genetics and crime: integrating new genomic discoveries into psychological research about antisocial behavior
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945301/
https://www.ncbi.nlm.nih.gov/pubmed/29513605
http://dx.doi.org/10.1177/0956797617744542
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