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Systemic inflammatory status predict the outcome of k-RAS WT metastatic colorectal cancer patients receiving the thymidylate synthase poly-epitope-peptide anticancer vaccine

TSPP is an anticancer poly-epitope peptide vaccine to thymidylate synthase, recently investigated in the multi-arm phase Ib TSPP/VAC1 trial. TSPP vaccination induced immune-biological effects and showed antitumor activity in metastatic colorectal cancer (mCRC) patients and other malignancies. Progre...

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Detalles Bibliográficos
Autores principales: Correale, Pierpaolo, Botta, Cirino, Staropoli, Nicoletta, Nardone, Valerio, Pastina, Pierpaolo, Ulivieri, Cristina, Gandolfo, Claudia, Baldari, Tatiana Cosima, Lazzi, Stefano, Ciliberto, Domenico, Giannicola, Rocco, Fioravanti, Antonella, Giordano, Antonio, Zappavigna, Silvia, Caraglia, Michele, Tassone, Pierfrancesco, Pirtoli, Luigi, Cusi, Maria Grazia, Tagliaferri, Pierosandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945541/
https://www.ncbi.nlm.nih.gov/pubmed/29755670
http://dx.doi.org/10.18632/oncotarget.24993