Structural determinants influencing halogen bonding: a case study on azinesulfonamide analogs of aripiprazole as 5-HT(1A), 5-HT(7), and D(2) receptor ligands

A series of azinesulfonamide derivatives of long-chain arylpiperazines with variable-length alkylene spacers between sulfonamide and 4-arylpiperazine moiety is designed, synthesized, and biologically evaluated. In vitro methods are used to determine their affinity for serotonin 5-HT(1A), 5-HT(6), 5-...

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Detalles Bibliográficos
Autores principales: Marciniec, Krzysztof, Kurczab, Rafał, Książek, Maria, Bębenek, Ewa, Chrobak, Elwira, Satała, Grzegorz, Bojarski, Andrzej J., Kusz, Joachim, Zajdel, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945563/
https://www.ncbi.nlm.nih.gov/pubmed/29748774
http://dx.doi.org/10.1186/s13065-018-0422-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945563/
https://www.ncbi.nlm.nih.gov/pubmed/29748774
http://dx.doi.org/10.1186/s13065-018-0422-5

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