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NVP-BEZ235, a dual PI3K-mTOR inhibitor, suppresses the growth of FaDu hypopharyngeal squamous cell carcinoma and has a synergistic effect with Cisplatin

NVP-BEZ235 is a dual phosphoinositide 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) inhibitor. A dual approach targeting more than one downstream effector is a promising strategy for treating cancers. The aim of this study was to evaluate the effect of NVP-BEZ235 in treating FaDu hypopharynge...

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Detalles Bibliográficos
Autores principales:	Hsu, Cheng-Ming, Lin, Pai-Mei, Tsai, Yao-Te, Tsai, Ming-Shao, Tseng, Chun-Han, Lin, Sheng-Fung, Yang, Ming-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945618/ https://www.ncbi.nlm.nih.gov/pubmed/29760955 http://dx.doi.org/10.1038/s41420-018-0060-7

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