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Hyperglycemia potentiates a shift from apoptosis to RIP1-dependent necroptosis

Apoptosis and necroptosis are the primary modes of eukaryotic cell death, with apoptosis being non-inflammatory while necroptosis is highly inflammatory. We previously demonstrated that, once activated, necroptosis is enhanced by hyperglycemia in several cell types. Here, we determine if hyperglycem...

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Detalles Bibliográficos
Autores principales: McCaig, William D., Patel, Payal S., Sosunov, Sergey A., Shakerley, Nicole L., Smiraglia, Tori A., Craft, Miranda M., Walker, Katharine M., Deragon, Matthew A., Ten, Vadim S., LaRocca, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945624/
https://www.ncbi.nlm.nih.gov/pubmed/29760953
http://dx.doi.org/10.1038/s41420-018-0058-1