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MiR-455-3p inhibits the degenerate process of chondrogenic differentiation through modification of DNA methylation
The aim of this work was to determine whether miR-455-3p regulates DNA methylation during chondrogenic differentiation of hMSCs. The expression of miR-455-3p and de novo methyltransferase DNMT3A was assessed in micromass culture of hBMSCs, which induced chondrogenic differentiation in vitro, and in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945650/ https://www.ncbi.nlm.nih.gov/pubmed/29748607 http://dx.doi.org/10.1038/s41419-018-0565-2 |