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CD47-ligation induced cell death in T-acute lymphoblastic leukemia

CD47 is a cell-surface marker well recognized for its anti-phagocytic functions. As such, an emerging avenue for targeted cancer therapies involves neutralizing the anti-phagocytic function using monoclonal antibodies (mAbs) to enhance tumour cell immunogenicity. A lesser known consequence of CD47 r...

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Detalles Bibliográficos
Autores principales: Leclair, Pascal, Liu, Chi-Chao, Monajemi, Mahdis, Reid, Gregor S., Sly, Laura M., Lim, Chinten James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945676/
https://www.ncbi.nlm.nih.gov/pubmed/29748606
http://dx.doi.org/10.1038/s41419-018-0601-2