Cargando…

CD47-ligation induced cell death in T-acute lymphoblastic leukemia

CD47 is a cell-surface marker well recognized for its anti-phagocytic functions. As such, an emerging avenue for targeted cancer therapies involves neutralizing the anti-phagocytic function using monoclonal antibodies (mAbs) to enhance tumour cell immunogenicity. A lesser known consequence of CD47 r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leclair, Pascal, Liu, Chi-Chao, Monajemi, Mahdis, Reid, Gregor S., Sly, Laura M., Lim, Chinten James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945676/ https://www.ncbi.nlm.nih.gov/pubmed/29748606 http://dx.doi.org/10.1038/s41419-018-0601-2

Ejemplares similares

Integrins and ERp57 Coordinate to Regulate Cell Surface Calreticulin in Immunogenic Cell Death
por: Liu, Chi-Chao, et al.
Publicado: (2019)

CD47 (Cluster of differentiation 47): an anti-phagocytic receptor with a multitude of signaling functions
por: Leclair, Pascal, et al.
Publicado: (2020)

CD47-Independent Effects Mediated by the TSP-Derived 4N1K Peptide
por: Leclair, Pascal, et al.
Publicado: (2014)

Peptide analogues PKHB1 and 4N1K induce cell death through CD47‐independent mechanisms
por: Leclair, Pascal, et al.
Publicado: (2020)

HIV-1 Vpu Promotes Phagocytosis of Infected CD4(+) T Cells by Macrophages through Downregulation of CD47
por: Cong, Lijun, et al.
Publicado: (2021)

CD47 agonist peptide PKHB1 induces immunogenic cell death in T‐cell acute lymphoblastic leukemia cells
por: Uscanga‐Palomeque, Ashanti Concepción, et al.
Publicado: (2018)

α-Integrin expression and function modulates presentation of cell surface calreticulin
por: Liu, C-C, et al.
Publicado: (2016)

A cross‐standardized flow cytometry platform to assess phenotypic stability in precursor B‐cell acute lymphoblastic leukemia (B‐ALL) xenografts
por: Rolf, Nina, et al.
Publicado: (2021)

CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity
por: Husak, Z, et al.
Publicado: (2012)

Cd47 Ligation Selectively Downregulates Human Interleukin 12 Production
por: Armant, Myriam, et al.
Publicado: (1999)

Targeting the gp130/STAT3 Axis Attenuates Tumor Microenvironment Mediated Chemoresistance in Group 3 Medulloblastoma Cells
por: Sreenivasan, Lakshana, et al.
Publicado: (2022)

CD47 expression in acute myeloid leukemia varies according to genotype
por: Marra, Andrea, et al.
Publicado: (2023)

Autocrine IL-6/STAT3 signaling aids development of acquired drug resistance in Group 3 medulloblastoma
por: Sreenivasan, Lakshana, et al.
Publicado: (2020)

CD1d levels in peripheral blood of patients with acute myeloid leukemia and acute lymphoblastic leukemia
por: GUO, WENJIAN, et al.
Publicado: (2014)

The Expression and Prognostic Impact of CD95 Death Receptor and CD20, CD34 and CD44 Differentiation Markers in Pediatric Acute Lymphoblastic Leukemia
por: M. Kamazani, Fatemeh, et al.
Publicado: (2014)

Harnessing Macrophages through the Blockage of CD47: Implications for Acute Myeloid Leukemia
por: Melo Garcia, Luciana, et al.
Publicado: (2021)

Targeting Menin and CD47 to Address Unmet Needs in Acute Myeloid Leukemia
por: Matthews, Andrew H., et al.
Publicado: (2022)

CD34 and CD38 are prognostic biomarkers for acute B lymphoblastic leukemia
por: Jiang, Zhiwu, et al.
Publicado: (2016)

Prognostic Role of CD200 in Acute Lymphoblastic Leukemia Patients
por: Khalil, Mohamed, et al.
Publicado: (2023)

CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals
por: Li, Yang, et al.
Publicado: (2022)

Phenotyping and Target Expression Profiling of CD34(+)/CD38(−) and CD34(+)/CD38(+) Stem- and Progenitor cells in Acute Lymphoblastic Leukemia
por: Blatt, Katharina, et al.
Publicado: (2018)

Centrosome Amplification Is a Potential Molecular Target in Paediatric Acute Lymphoblastic Leukemia
por: Guo, Meiyun, et al.
Publicado: (2022)

Can CD34(+)CD38(−) lymphoblasts, as likely leukemia stem cells, be a prognostic factor in B-cell precursor acute lymphoblastic leukemia in children?
por: Stolpa, Weronika, et al.
Publicado: (2023)

Acute lymphoblastic leukemia
por: Schrappe, Martin
Publicado: (2018)

Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8(+) T Cells
por: Monajemi, Mahdis, et al.
Publicado: (2014)

Investigating CD99 Expression in Leukemia Propagating Cells in Childhood T Cell Acute Lymphoblastic Leukemia
por: Cox, Charlotte V., et al.
Publicado: (2016)

Childhood acute lymphoblastic leukemia with hyperleukocytosis at presentation
por: Kong, Seom Gim, et al.
Publicado: (2014)

Modulation of CD19 surface expression in B cell acute lymphoblastic leukemia
Publicado: (2022)

A case of acute myelomonocytic leukemia morphologically mimicking lymphoblastic leukemia
por: Ni, Sao‐Chih, et al.
Publicado: (2023)

Targetable lesions and proteomes predict therapy sensitivity through disease evolution in pediatric acute lymphoblastic leukemia
por: Lorentzian, Amanda C., et al.
Publicado: (2023)

Prethymic Cytoplasmic CD3 Negative Acute Lymphoblastic Leukemia or Acute Undifferentiated Leukemia: A Case Report
por: Cannizzo, Elisa, et al.
Publicado: (2011)

Acute lymphoblastic leukemia in adults
por: Ribera, Josep-Maria
Publicado: (2011)

Pediatric acute lymphoblastic leukemia
por: Inaba, Hiroto, et al.
Publicado: (2020)

PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways
por: Uzozie, Anuli C., et al.
Publicado: (2021)

Combination therapy with proteasome inhibitors and TLR agonists enhances tumour cell death and IL-1β production
por: Tang, Anthony C, et al.
Publicado: (2018)

Immunophenotypic markers in adult acute lymphoblastic leukemia: the prognostic significance of CD20 and TdT expression
por: Kim, Dae-Young, et al.
Publicado: (2015)

Rapid Identification of Key Copy Number Alterations in B- and T-Cell Acute Lymphoblastic Leukemia by Digital Multiplex Ligation-Dependent Probe Amplification
por: Thakral, Deepshi, et al.
Publicado: (2019)

Aberrant expression of CD133 and CD82 in patients with pediatric acute lymphoblastic leukemia and the clinical significance
por: Ji, Hongyan, et al.
Publicado: (2017)

The Differential Expression of CD47 may be Related to the Pathogenesis From Myelodysplastic Syndromes to Acute Myeloid Leukemia
por: Yan, Xiao, et al.
Publicado: (2022)

PB1794: EFFECT OF HYPOXIA ON CD47 EXPRESSION IN HUMAN ACUTE MYELOID LEUKEMIA CELL LINES
por: Wang, C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p3jdig64fs0bl7pprnturi1s9b