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Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells
Affective disorders such as major depression and bipolar disorder are among the most prevalent forms of mental illness and their etiologies involve complex interactions between genetic and environmental risk factors. Over the past ten years, several genome wide association studies (GWAS) have identi...
Autores principales: | Michels, Susanne, Ganjam, Goutham K., Martins, Helena, Schratt, Gerhard M., Wöhr, Markus, Schwarting, Rainer K. W., Culmsee, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945680/ https://www.ncbi.nlm.nih.gov/pubmed/29760952 http://dx.doi.org/10.1038/s41420-018-0061-6 |
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