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Exploring DNA quality of single cells for genome analysis with simultaneous whole-genome amplification
Single cell genome analysis methods are powerful tools to define features of single cells and to identify differences between them. Since the DNA amount of a single cell is very limited, cellular DNA usually needs to be amplified by whole-genome amplification before being subjected to further analys...
Autores principales: | Bäumer, Christiane, Fisch, Evelyn, Wedler, Holger, Reinecke, Frank, Korfhage, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945709/ https://www.ncbi.nlm.nih.gov/pubmed/29748573 http://dx.doi.org/10.1038/s41598-018-25895-7 |
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