Relationship Between Homodimeric Glucocorticoid Receptor and Transcriptional Regulation Assessed via an In Vitro Fluorescence Correlation Spectroscopy-Microwell System

Glucocorticoid receptor (GR) is a hormone-activated transcription regulatory protein involved in metabolism as well as adrenocortical responses to psychosocial stress. Ligand-activated GR localizes to the nucleus, where GR homodimers regulate gene transcription via direct binding to glucocorticoid r...

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Detalles Bibliográficos
Autores principales: Oasa, Sho, Mikuni, Shintaro, Yamamoto, Johtaro, Kurosaki, Tsumugi, Yamashita, Daisuke, Kinjo, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945783/
https://www.ncbi.nlm.nih.gov/pubmed/29748590
http://dx.doi.org/10.1038/s41598-018-25393-w

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