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Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment
In this paper we analyze two stochastic versions of one of the simplest classes of contagion models, namely so-called SIS models. Several formulations of such models, based on stochastic differential equations, have been recently discussed in literature, mainly with a focus on the existence and uniq...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945815/ https://www.ncbi.nlm.nih.gov/pubmed/29773967 http://dx.doi.org/10.1007/s10100-018-0526-y |
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author | Kovacevic, Raimund M. |
author_facet | Kovacevic, Raimund M. |
author_sort | Kovacevic, Raimund M. |
collection | PubMed |
description | In this paper we analyze two stochastic versions of one of the simplest classes of contagion models, namely so-called SIS models. Several formulations of such models, based on stochastic differential equations, have been recently discussed in literature, mainly with a focus on the existence and uniqueness of stationary distributions. With applicability in view, the present paper uses the Fokker–Planck equations related to SIS stochastic differential equations, not only in order to derive basic facts, but also to derive explicit expressions for stationary densities and further characteristics related to the asymptotic behaviour. Two types of models are analyzed here: The first one is a version of the SIS model with external parameter noise and saturated incidence. The second one is based on the Kramers–Moyal approximation of the simple SIS Markov chain model, which leads to a model with scaled additive noise. In both cases we analyze the asymptotic behaviour, which leads to limiting stationary distributions in the first case and limiting quasistationary distributions in the second case. Finally, we use the derived properties for analyzing the decision problem of choosing the cost-optimal level of treatment intensity. |
format | Online Article Text |
id | pubmed-5945815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-59458152018-05-15 Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment Kovacevic, Raimund M. Cent Eur J Oper Res Original Paper In this paper we analyze two stochastic versions of one of the simplest classes of contagion models, namely so-called SIS models. Several formulations of such models, based on stochastic differential equations, have been recently discussed in literature, mainly with a focus on the existence and uniqueness of stationary distributions. With applicability in view, the present paper uses the Fokker–Planck equations related to SIS stochastic differential equations, not only in order to derive basic facts, but also to derive explicit expressions for stationary densities and further characteristics related to the asymptotic behaviour. Two types of models are analyzed here: The first one is a version of the SIS model with external parameter noise and saturated incidence. The second one is based on the Kramers–Moyal approximation of the simple SIS Markov chain model, which leads to a model with scaled additive noise. In both cases we analyze the asymptotic behaviour, which leads to limiting stationary distributions in the first case and limiting quasistationary distributions in the second case. Finally, we use the derived properties for analyzing the decision problem of choosing the cost-optimal level of treatment intensity. Springer Berlin Heidelberg 2018-02-07 2018 /pmc/articles/PMC5945815/ /pubmed/29773967 http://dx.doi.org/10.1007/s10100-018-0526-y Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Original Paper Kovacevic, Raimund M. Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title | Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title_full | Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title_fullStr | Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title_full_unstemmed | Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title_short | Stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
title_sort | stochastic contagion models without immunity: their long term behaviour and the optimal level of treatment |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945815/ https://www.ncbi.nlm.nih.gov/pubmed/29773967 http://dx.doi.org/10.1007/s10100-018-0526-y |
work_keys_str_mv | AT kovacevicraimundm stochasticcontagionmodelswithoutimmunitytheirlongtermbehaviourandtheoptimalleveloftreatment |