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Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells
During embryonic development, differentiation of cochlear progenitor cells into hair cells (HCs) or supporting cells (SCs) is partially controlled through Notch signaling. Many studies have shown that inhibition of Notch signaling allows SCs to convert into HCs in both normal and drug damaged neonat...
Autores principales: | McGovern, Melissa M., Zhou, Luyi, Randle, Michelle R., Cox, Brandon C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945818/ https://www.ncbi.nlm.nih.gov/pubmed/29780306 http://dx.doi.org/10.3389/fncel.2018.00120 |
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