Cargando…
NHR‐49/HNF4 integrates regulation of fatty acid metabolism with a protective transcriptional response to oxidative stress and fasting
Endogenous and exogenous stresses elicit transcriptional responses that limit damage and promote cell/organismal survival. Like its mammalian counterparts, hepatocyte nuclear factor 4 (HNF4) and peroxisome proliferator‐activated receptor α (PPARα), Caenorhabditis elegans NHR‐49 is a well‐established...
Autores principales: | Goh, Grace Y. S., Winter, Johnathan J., Bhanshali, Forum, Doering, Kelsie R. S., Lai, Regina, Lee, Kayoung, Veal, Elizabeth A., Taubert, Stefan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946062/ https://www.ncbi.nlm.nih.gov/pubmed/29508513 http://dx.doi.org/10.1111/acel.12743 |
Ejemplares similares
-
Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegans
por: Doering, Kelsie R. S., et al.
Publicado: (2023) -
Gain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally Distinct
por: Lee, Kayoung, et al.
Publicado: (2016) -
Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans
por: Doering, Kelsie RS, et al.
Publicado: (2022) -
The Caenorhabditis elegans Oxidative Stress Response Requires the NHR-49 Transcription Factor
por: Hu, Queenie, et al.
Publicado: (2018) -
Nuclear receptors NHR-49 and NHR-79 promote peroxisome proliferation to compensate for aldehyde dehydrogenase deficiency in C. elegans
por: Zeng, Lidan, et al.
Publicado: (2021)