Pathways of airway oxidant formation by house dust mite allergens and viral RNA converge through myosin motors, pannexons and Toll‐like receptor 4

INTRODUCTION: Intracellular reactive oxidant species (ROS) are generated in human airway epithelial cells by the prothrombinase action of Group 1 house dust mite (HDM) allergens and by ligation of viral RNA sensor Toll‐like receptors (TLRs). We explored signaling convergence between HDM allergens an...

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Detalles Bibliográficos
Autores principales: Zhang, Jihui, Chen, Jie, Mangat, Shannon C., Perera Baruhupolage, Chathuri, Garrod, David R., Robinson, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946151/
https://www.ncbi.nlm.nih.gov/pubmed/29542272
http://dx.doi.org/10.1002/iid3.216

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