Lysophosphatidic Acid Signaling in Obesity and Insulin Resistance

Although simple in structure, lysophosphatidic acid (LPA) is a potent bioactive lipid that profoundly influences cellular signaling and function upon binding to G protein-coupled receptors (LPA1-6). The majority of circulating LPA is produced by the secreted enzyme autotaxin (ATX). Alterations in LP...

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Detalles Bibliográficos
Autores principales: D’Souza, Kenneth, Paramel, Geena V., Kienesberger, Petra C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946184/
https://www.ncbi.nlm.nih.gov/pubmed/29570618
http://dx.doi.org/10.3390/nu10040399

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