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Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal

Single and multiple variable regression analyses were conducted using data from stratified, cluster sample design, iodine surveys in India, Ghana, and Senegal to identify factors associated with urinary iodine concentration (UIC) among women of reproductive age (WRA) at the national and sub-national...

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Autores principales: Knowles, Jacky, Kupka, Roland, Dumble, Sam, Garrett, Greg S., Pandav, Chandrakant S., Yadav, Kapil, Touré, Ndeye Khady, Foriwa Amoaful, Esi, Gorstein, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946301/
https://www.ncbi.nlm.nih.gov/pubmed/29690505
http://dx.doi.org/10.3390/nu10040516
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author Knowles, Jacky
Kupka, Roland
Dumble, Sam
Garrett, Greg S.
Pandav, Chandrakant S.
Yadav, Kapil
Touré, Ndeye Khady
Foriwa Amoaful, Esi
Gorstein, Jonathan
author_facet Knowles, Jacky
Kupka, Roland
Dumble, Sam
Garrett, Greg S.
Pandav, Chandrakant S.
Yadav, Kapil
Touré, Ndeye Khady
Foriwa Amoaful, Esi
Gorstein, Jonathan
author_sort Knowles, Jacky
collection PubMed
description Single and multiple variable regression analyses were conducted using data from stratified, cluster sample design, iodine surveys in India, Ghana, and Senegal to identify factors associated with urinary iodine concentration (UIC) among women of reproductive age (WRA) at the national and sub-national level. Subjects were survey household respondents, typically WRA. For all three countries, UIC was significantly different (p < 0.05) by household salt iodine category. Other significant differences were by strata and by household vulnerability to poverty in India and Ghana. In multiple variable regression analysis, UIC was significantly associated with strata and household salt iodine category in India and Ghana (p < 0.001). Estimated UIC was 1.6 (95% confidence intervals (CI) 1.3, 2.0) times higher (India) and 1.4 (95% CI 1.2, 1.6) times higher (Ghana) among WRA from households using adequately iodised salt than among WRA from households using non-iodised salt. Other significant associations with UIC were found in India, with having heard of iodine deficiency (1.2 times higher; CI 1.1, 1.3; p < 0.001) and having improved dietary diversity (1.1 times higher, CI 1.0, 1.2; p = 0.015); and in Ghana, with the level of tomato paste consumption the previous week (p = 0.029) (UIC for highest consumption level was 1.2 times lowest level; CI 1.1, 1.4). No significant associations were found in Senegal. Sub-national data on iodine status are required to assess equity of access to optimal iodine intake and to develop strategic responses as needed.
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spelling pubmed-59463012018-05-15 Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal Knowles, Jacky Kupka, Roland Dumble, Sam Garrett, Greg S. Pandav, Chandrakant S. Yadav, Kapil Touré, Ndeye Khady Foriwa Amoaful, Esi Gorstein, Jonathan Nutrients Article Single and multiple variable regression analyses were conducted using data from stratified, cluster sample design, iodine surveys in India, Ghana, and Senegal to identify factors associated with urinary iodine concentration (UIC) among women of reproductive age (WRA) at the national and sub-national level. Subjects were survey household respondents, typically WRA. For all three countries, UIC was significantly different (p < 0.05) by household salt iodine category. Other significant differences were by strata and by household vulnerability to poverty in India and Ghana. In multiple variable regression analysis, UIC was significantly associated with strata and household salt iodine category in India and Ghana (p < 0.001). Estimated UIC was 1.6 (95% confidence intervals (CI) 1.3, 2.0) times higher (India) and 1.4 (95% CI 1.2, 1.6) times higher (Ghana) among WRA from households using adequately iodised salt than among WRA from households using non-iodised salt. Other significant associations with UIC were found in India, with having heard of iodine deficiency (1.2 times higher; CI 1.1, 1.3; p < 0.001) and having improved dietary diversity (1.1 times higher, CI 1.0, 1.2; p = 0.015); and in Ghana, with the level of tomato paste consumption the previous week (p = 0.029) (UIC for highest consumption level was 1.2 times lowest level; CI 1.1, 1.4). No significant associations were found in Senegal. Sub-national data on iodine status are required to assess equity of access to optimal iodine intake and to develop strategic responses as needed. MDPI 2018-04-21 /pmc/articles/PMC5946301/ /pubmed/29690505 http://dx.doi.org/10.3390/nu10040516 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Knowles, Jacky
Kupka, Roland
Dumble, Sam
Garrett, Greg S.
Pandav, Chandrakant S.
Yadav, Kapil
Touré, Ndeye Khady
Foriwa Amoaful, Esi
Gorstein, Jonathan
Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title_full Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title_fullStr Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title_full_unstemmed Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title_short Regression Analysis to Identify Factors Associated with Urinary Iodine Concentration at the Sub-National Level in India, Ghana, and Senegal
title_sort regression analysis to identify factors associated with urinary iodine concentration at the sub-national level in india, ghana, and senegal
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946301/
https://www.ncbi.nlm.nih.gov/pubmed/29690505
http://dx.doi.org/10.3390/nu10040516
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