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Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study
The usage of prophylactic oral antibiotics following distal hypospadias repair with stenting has been recently challenged. This study evaluated the incidence of symptomatic urinary tract infections (UTIs) following stented, distal hypospadias repair and the impact of prophylactic antibiotic therapy....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946338/ https://www.ncbi.nlm.nih.gov/pubmed/29761139 http://dx.doi.org/10.1177/2333794X18770074 |
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author | Canon, Stephen Marquette, Mary K. Crane, Adam Patel, Ashay Zamilpa, Ismael Bai, Shasha |
author_facet | Canon, Stephen Marquette, Mary K. Crane, Adam Patel, Ashay Zamilpa, Ismael Bai, Shasha |
author_sort | Canon, Stephen |
collection | PubMed |
description | The usage of prophylactic oral antibiotics following distal hypospadias repair with stenting has been recently challenged. This study evaluated the incidence of symptomatic urinary tract infections (UTIs) following stented, distal hypospadias repair and the impact of prophylactic antibiotic therapy. Subjects 0 to 5 years of age with distal hypospadias were randomized to either Group 1 (antibiotics) or Group 2 (no prophylactic therapy). Urinalysis/urine culture was obtained intraoperatively with no preoperative antibiotics given. Phone interviews at 1 month and 3 months after surgery were done. Forty-eight patients were successfully randomized to either Group 1 (24) or Group 2 (24). The incidence of symptomatic UTI in this pilot study is low, and prophylactic antibiotic therapy does not appear to lower the incidence of symptomatic UTI. A larger, randomized, multicenter trial is needed to determine whether antibiotic prophylaxis reduces the risk of symptomatic UTIs following stented, distal hypospadias repair. |
format | Online Article Text |
id | pubmed-5946338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-59463382018-05-14 Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study Canon, Stephen Marquette, Mary K. Crane, Adam Patel, Ashay Zamilpa, Ismael Bai, Shasha Glob Pediatr Health Original Article The usage of prophylactic oral antibiotics following distal hypospadias repair with stenting has been recently challenged. This study evaluated the incidence of symptomatic urinary tract infections (UTIs) following stented, distal hypospadias repair and the impact of prophylactic antibiotic therapy. Subjects 0 to 5 years of age with distal hypospadias were randomized to either Group 1 (antibiotics) or Group 2 (no prophylactic therapy). Urinalysis/urine culture was obtained intraoperatively with no preoperative antibiotics given. Phone interviews at 1 month and 3 months after surgery were done. Forty-eight patients were successfully randomized to either Group 1 (24) or Group 2 (24). The incidence of symptomatic UTI in this pilot study is low, and prophylactic antibiotic therapy does not appear to lower the incidence of symptomatic UTI. A larger, randomized, multicenter trial is needed to determine whether antibiotic prophylaxis reduces the risk of symptomatic UTIs following stented, distal hypospadias repair. SAGE Publications 2018-04-30 /pmc/articles/PMC5946338/ /pubmed/29761139 http://dx.doi.org/10.1177/2333794X18770074 Text en © The Author(s) 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Canon, Stephen Marquette, Mary K. Crane, Adam Patel, Ashay Zamilpa, Ismael Bai, Shasha Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title | Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title_full | Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title_fullStr | Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title_full_unstemmed | Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title_short | Prophylactic Antibiotics After Stented, Distal Hypospadias Repair: Randomized Pilot Study |
title_sort | prophylactic antibiotics after stented, distal hypospadias repair: randomized pilot study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946338/ https://www.ncbi.nlm.nih.gov/pubmed/29761139 http://dx.doi.org/10.1177/2333794X18770074 |
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