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Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli

BACKGROUND: Fibroblast apoptosis is a critical component of normal repair and the acquisition of an apoptosis-resistant phenotype contributes to the pathogenesis of fibrotic repair. Fibroblasts from fibrotic lungs of humans and mice demonstrate resistance to apoptosis induced by Fas-ligand and prior...

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Detalles Bibliográficos
Autores principales:	Dodi, Amos E., Ajayi, Iyabode O., Chang, Christine, Beard, Meghan, Ashley, Shanna L., Huang, Steven K., Thannickal, Victor J., Tschumperlin, Daniel J., Sisson, Thomas H., Horowitz, Jeffrey C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946418/ https://www.ncbi.nlm.nih.gov/pubmed/29747634 http://dx.doi.org/10.1186/s12931-018-0801-4

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