Selective modulation of local linkages between active transcription and oxidative demethylation activity shapes cardiomyocyte-specific gene-body epigenetic status in mice

BACKGROUND: Cell-type-specific genes exhibit heterogeneity in genomic contexts and may be subject to different epigenetic regulations through different gene transcriptional processes depending on the cell type involved. The gene-body regions (GBRs) of some cardiomyocyte (CM)-specific genes are long...

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Detalles Bibliográficos
Autores principales: Oda, Mayumi, Wakabayashi, Shunichi, Ari Wijetunga, N., Yuasa, Shinsuke, Enomoto, Hirokazu, Kaneda, Ruri, Yoon, Sung Han, Mittal, Nishant, Jing, Qiang, Suzuki, Masako, Greally, John M., Fukuda, Keiichi, Makino, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946493/
https://www.ncbi.nlm.nih.gov/pubmed/29747586
http://dx.doi.org/10.1186/s12864-018-4752-4

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