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Predicting multi-level drug response with gene expression profile in multiple myeloma using hierarchical ordinal regression

BACKGROUND: Multiple myeloma (MM), like other cancers, is caused by the accumulation of genetic abnormalities. Heterogeneity exists in the patients’ response to treatments, for example, bortezomib. This urges efforts to identify biomarkers from numerous molecular features and build predictive models...

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Detalles Bibliográficos
Autores principales:	Zhang, Xinyan, Li, Bingzong, Han, Huiying, Song, Sha, Xu, Hongxia, Hong, Yating, Yi, Nengjun, Zhuang, Wenzhuo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946496/ https://www.ncbi.nlm.nih.gov/pubmed/29747599 http://dx.doi.org/10.1186/s12885-018-4483-6

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