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Presacral myelolipoma as a possible parasymptom of cancer: A case report

Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements. Presacral myelolipomas can occur in patients with a medical history of malignancy, steroid use, and/or endocrine disorders including diabetes mellitus. A 65-year-old man with no...

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Autores principales: Sakamoto, Akio, Nagamatsu, Iori, Shiba, Eisuke, Okamoto, Takeshi, Hisaoka, Masanori, Matsuda, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946595/
https://www.ncbi.nlm.nih.gov/pubmed/29760871
http://dx.doi.org/10.1177/2036361318772124
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author Sakamoto, Akio
Nagamatsu, Iori
Shiba, Eisuke
Okamoto, Takeshi
Hisaoka, Masanori
Matsuda, Shuichi
author_facet Sakamoto, Akio
Nagamatsu, Iori
Shiba, Eisuke
Okamoto, Takeshi
Hisaoka, Masanori
Matsuda, Shuichi
author_sort Sakamoto, Akio
collection PubMed
description Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements. Presacral myelolipomas can occur in patients with a medical history of malignancy, steroid use, and/or endocrine disorders including diabetes mellitus. A 65-year-old man with no specific medical history experienced temporal abdominal pain without bowel symptoms that lasted a few hours. By the time he visited a hospital, the pain had diminished. Computed tomography failed to detect any abnormality in the abdominal or pelvic organs that would have caused the abdominal pain but revealed a lesion 4 cm in diameter in the frontal sacrum. Magnetic resonance imaging showed that the lesion contained fat elements with a high signal intensity on T1- and T2-weighted images, which was decreased on fat-suppression T2-weighted images. Computed tomography–guided biopsy and imaging allowed a diagnosis of presacral myelolipoma. After 3 months, hematochezia was observed, and follow-up examination revealed rectal carcinoma with multiple lung metastases. He died due to spread of the cancer despite chemotherapy, 6 months after the cancer was found. Considering the possible association between presacral myelolipoma and cancer, presacral myelolipoma might be a cancer parasymptom. Checking for possible malignancy may therefore be warranted in patients with presacral myelolipoma, especially in those without diabetes mellitus.
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spelling pubmed-59465952018-05-14 Presacral myelolipoma as a possible parasymptom of cancer: A case report Sakamoto, Akio Nagamatsu, Iori Shiba, Eisuke Okamoto, Takeshi Hisaoka, Masanori Matsuda, Shuichi Rare Tumors Article Presacral myelolipomas are rare, benign, asymptomatic tumors composed of mature adipose tissue and hematopoietic elements. Presacral myelolipomas can occur in patients with a medical history of malignancy, steroid use, and/or endocrine disorders including diabetes mellitus. A 65-year-old man with no specific medical history experienced temporal abdominal pain without bowel symptoms that lasted a few hours. By the time he visited a hospital, the pain had diminished. Computed tomography failed to detect any abnormality in the abdominal or pelvic organs that would have caused the abdominal pain but revealed a lesion 4 cm in diameter in the frontal sacrum. Magnetic resonance imaging showed that the lesion contained fat elements with a high signal intensity on T1- and T2-weighted images, which was decreased on fat-suppression T2-weighted images. Computed tomography–guided biopsy and imaging allowed a diagnosis of presacral myelolipoma. After 3 months, hematochezia was observed, and follow-up examination revealed rectal carcinoma with multiple lung metastases. He died due to spread of the cancer despite chemotherapy, 6 months after the cancer was found. Considering the possible association between presacral myelolipoma and cancer, presacral myelolipoma might be a cancer parasymptom. Checking for possible malignancy may therefore be warranted in patients with presacral myelolipoma, especially in those without diabetes mellitus. SAGE Publications 2018-04-23 /pmc/articles/PMC5946595/ /pubmed/29760871 http://dx.doi.org/10.1177/2036361318772124 Text en © The Author(s) 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Article
Sakamoto, Akio
Nagamatsu, Iori
Shiba, Eisuke
Okamoto, Takeshi
Hisaoka, Masanori
Matsuda, Shuichi
Presacral myelolipoma as a possible parasymptom of cancer: A case report
title Presacral myelolipoma as a possible parasymptom of cancer: A case report
title_full Presacral myelolipoma as a possible parasymptom of cancer: A case report
title_fullStr Presacral myelolipoma as a possible parasymptom of cancer: A case report
title_full_unstemmed Presacral myelolipoma as a possible parasymptom of cancer: A case report
title_short Presacral myelolipoma as a possible parasymptom of cancer: A case report
title_sort presacral myelolipoma as a possible parasymptom of cancer: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946595/
https://www.ncbi.nlm.nih.gov/pubmed/29760871
http://dx.doi.org/10.1177/2036361318772124
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