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mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription

mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and translation. We report that the mammalian mRNA cap methyltransferase, RNMT-RAM, promotes RNA Pol II transcription independent of mRNA capping and translation. In cells, sublethal suppressio...

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Detalles Bibliográficos
Autores principales:	Varshney, Dhaval, Lombardi, Olivia, Schweikert, Gabriele, Dunn, Sianadh, Suska, Olga, Cowling, Victoria H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946721/ https://www.ncbi.nlm.nih.gov/pubmed/29719263 http://dx.doi.org/10.1016/j.celrep.2018.04.004

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