Cargando…

Chiron: translating nanopore raw signal directly into nucleotide sequence using deep learning

Sequencing by translocating DNA fragments through an array of nanopores is a rapidly maturing technology that offers faster and cheaper sequencing than other approaches. However, accurately deciphering the DNA sequence from the noisy and complex electrical signal is challenging. Here, we report Chir...

Descripción completa

Detalles Bibliográficos
Autores principales: Teng, Haotian, Cao, Minh Duc, Hall, Michael B, Duarte, Tania, Wang, Sheng, Coin, Lachlan J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946831/
https://www.ncbi.nlm.nih.gov/pubmed/29648610
http://dx.doi.org/10.1093/gigascience/giy037