Synthesis and biological evaluation of aryl-oxadiazoles as inhibitors of Mycobacterium tuberculosis

Despite increased research efforts to find new treatments for tuberculosis in recent decades, compounds with novel mechanisms of action are still required. We previously identified a series of novel aryl-oxadiazoles with anti-tubercular activity specific for bacteria using butyrate as a carbon sourc...

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Detalles Bibliográficos
Autores principales: Martinez-Grau, Maria Angeles, Valcarcel, Isabel C. Gonzalez, Early, Julie V., Gessner, Richard Klaus, de Melo, Candice Soares, de la Nava, Eva Maria Martin, Korkegian, Aaron, Ovechkina, Yulia, Flint, Lindsay, Gravelle, Anisa, Cramer, Jeff W., Desai, Prashant V., Street, Leslie J., Odingo, Joshua, Masquelin, Thierry, Chibale, Kelly, Parish, Tanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946847/
https://www.ncbi.nlm.nih.gov/pubmed/29680666
http://dx.doi.org/10.1016/j.bmcl.2018.04.028

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