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Experimental maps of DNA structure at nucleotide resolution distinguish intrinsic from protein-induced DNA deformations

Recognition of DNA by proteins depends on DNA sequence and structure. Often unanswered is whether the structure of naked DNA persists in a protein–DNA complex, or whether protein binding changes DNA shape. While X-ray structures of protein–DNA complexes are numerous, the structure of naked cognate D...

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Detalles Bibliográficos
Autores principales:	Azad, Robert N, Zafiropoulos, Dana, Ober, Douglas, Jiang, Yining, Chiu, Tsu-Pei, Sagendorf, Jared M, Rohs, Remo, Tullius, Thomas D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946862/ https://www.ncbi.nlm.nih.gov/pubmed/29390080 http://dx.doi.org/10.1093/nar/gky033

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