Architecture and hydration of the arginine‐binding site of neuropilin‐1

Neuropilin‐1 (NRP1) is a transmembrane co‐receptor involved in binding interactions with variety of ligands and receptors, including receptor tyrosine kinases. Expression of NRP1 in several cancers correlates with cancer stages and poor prognosis. Thus, NRP1 has been considered a therapeutic target...

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Detalles Bibliográficos
Autores principales: Mota, Filipa, Fotinou, Constantina, Rana, Rohini R., Chan, A. W. Edith, Yelland, Tamas, Arooz, Mohamed T., O'Leary, Andrew P., Hutton, Jennie, Frankel, Paul, Zachary, Ian, Selwood, David, Djordjevic, Snezana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947257/
https://www.ncbi.nlm.nih.gov/pubmed/29430837
http://dx.doi.org/10.1111/febs.14405

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