Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

BACKGROUND. Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are often not performed in HCC. Blood‐derived circulating tumor DNA (ctDNA) analysis can identify somatic alterations, but its utility has not be...

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Detalles Bibliográficos
Autores principales: Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AlphaMed Press 2018
Materias:
Hepatobiliary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://www.ncbi.nlm.nih.gov/pubmed/29487225
http://dx.doi.org/10.1634/theoncologist.2017-0479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://www.ncbi.nlm.nih.gov/pubmed/29487225
http://dx.doi.org/10.1634/theoncologist.2017-0479

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