The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease

Alzheimer's disease (AD) is a devastating neurological disorder that still lacks an effective treatment, and this has stimulated an intense pursuit of disease‐modifying therapeutics. Given the increasingly recognized link between AD and defective brain insulin signaling, we investigated the act...

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Detalles Bibliográficos
Autores principales: Batista, Andre F, Forny‐Germano, Leticia, Clarke, Julia R, Lyra e Silva, Natalia M, Brito‐Moreira, Jordano, Boehnke, Susan E, Winterborn, Andrew, Coe, Brian C, Lablans, Ann, Vital, Juliana F, Marques, Suelen A, Martinez, Ana MB, Gralle, Matthias, Holscher, Christian, Klein, William L, Houzel, Jean‐Christophe, Ferreira, Sergio T, Munoz, Douglas P, De Felice, Fernanda G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947670/
https://www.ncbi.nlm.nih.gov/pubmed/29435980
http://dx.doi.org/10.1002/path.5056

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