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Structure of the mouse acidic amino acid decarboxylase GADL1

Pyridoxal 5′-phosphate (PLP) is a ubiquitous cofactor in various enzyme classes, including PLP-dependent decarboxylases. A recently discovered member of this class is glutamic acid decarboxylase-like protein 1 (GADL1), which lacks the activity to decarboxylate glutamate to γ-aminobutyrate, despite i...

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Detalles Bibliográficos
Autores principales: Raasakka, Arne, Mahootchi, Elaheh, Winge, Ingeborg, Luan, Weisha, Kursula, Petri, Haavik, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947694/
https://www.ncbi.nlm.nih.gov/pubmed/29372909
http://dx.doi.org/10.1107/S2053230X17017848