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System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation
Objective: Intraoperative radiotherapy (IORT) after surgical resection using a low‐kV‐X‐ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947750/ https://www.ncbi.nlm.nih.gov/pubmed/29484802 http://dx.doi.org/10.1002/rcs.1899 |
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author | Rothfuss, Andreas Oesterle, Oliver Bürgy, Daniel Nwankwo, Charles Schneider, Frank van Poelgeest, Auguste Wenz, Frederik Stallkamp, Jan Clausen, Sven |
author_facet | Rothfuss, Andreas Oesterle, Oliver Bürgy, Daniel Nwankwo, Charles Schneider, Frank van Poelgeest, Auguste Wenz, Frederik Stallkamp, Jan Clausen, Sven |
author_sort | Rothfuss, Andreas |
collection | PubMed |
description | Objective: Intraoperative radiotherapy (IORT) after surgical resection using a low‐kV‐X‐ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore suboptimal treatment for many patients. Methods: A system is proposed comprising an X‐ray source with an applicator for surface irradiation mounted on a robotic arm. This is controlled by an algorithm designed for planning the required continuous path, enabling irradiation of any desired shape with a controlled dose distribution. Results: The system is shown to be capable of irradiating areas composed of rectangles on a flat surface with a homogeneity index of less than 7% inside the targeted area. Conclusion: The presented results demonstrate the potential of the proposed setup to eliminate the current limitations, leading to better treatment of patients. |
format | Online Article Text |
id | pubmed-5947750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-59477502018-05-17 System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation Rothfuss, Andreas Oesterle, Oliver Bürgy, Daniel Nwankwo, Charles Schneider, Frank van Poelgeest, Auguste Wenz, Frederik Stallkamp, Jan Clausen, Sven Int J Med Robot Original Articles Objective: Intraoperative radiotherapy (IORT) after surgical resection using a low‐kV‐X‐ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore suboptimal treatment for many patients. Methods: A system is proposed comprising an X‐ray source with an applicator for surface irradiation mounted on a robotic arm. This is controlled by an algorithm designed for planning the required continuous path, enabling irradiation of any desired shape with a controlled dose distribution. Results: The system is shown to be capable of irradiating areas composed of rectangles on a flat surface with a homogeneity index of less than 7% inside the targeted area. Conclusion: The presented results demonstrate the potential of the proposed setup to eliminate the current limitations, leading to better treatment of patients. John Wiley and Sons Inc. 2018-02-27 2018-06 /pmc/articles/PMC5947750/ /pubmed/29484802 http://dx.doi.org/10.1002/rcs.1899 Text en © 2018 The Authors The International Journal of Medical Robotics and Computer Assisted Surgery Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Rothfuss, Andreas Oesterle, Oliver Bürgy, Daniel Nwankwo, Charles Schneider, Frank van Poelgeest, Auguste Wenz, Frederik Stallkamp, Jan Clausen, Sven System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title | System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title_full | System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title_fullStr | System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title_full_unstemmed | System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title_short | System and path planning algorithm for low‐kV X‐ray free‐form surface irradiation |
title_sort | system and path planning algorithm for low‐kv x‐ray free‐form surface irradiation |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947750/ https://www.ncbi.nlm.nih.gov/pubmed/29484802 http://dx.doi.org/10.1002/rcs.1899 |
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