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Validation of ligands in macromolecular structures determined by X-ray crystallography

Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) play a crucial role in structure-guided drug discovery and design, and also provide atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. The quali...

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Detalles Bibliográficos
Autores principales:	Smart, Oliver S., Horský, Vladimír, Gore, Swanand, Svobodová Vařeková, Radka, Bendová, Veronika, Kleywegt, Gerard J., Velankar, Sameer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2018
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947763/ https://www.ncbi.nlm.nih.gov/pubmed/29533230 http://dx.doi.org/10.1107/S2059798318002541

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