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Human Brain Organoids on a Chip Reveal the Physics of Folding

Human brain wrinkling has been implicated in neurodevelopmental disorders and yet its origins remain unknown. Polymer gel models suggest that wrinkling emerges spontaneously due to compression forces arising during differential swelling, but these ideas have not been tested in a living system. Here,...

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Detalles Bibliográficos
Autores principales:	Karzbrun, Eyal, Kshirsagar, Aditya, Cohen, Sidney R., Hanna, Jacob H., Reiner, Orly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947782/ https://www.ncbi.nlm.nih.gov/pubmed/29760764 http://dx.doi.org/10.1038/s41567-018-0046-7

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