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FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts

Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant accumulation of collagen-secreting myofibroblasts. Development of effective therapies is limited due to incomplete understanding of molecular mechanisms regulating myofibroblast expansion. FOXF1 transcription factor is expressed in res...

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Detalles Bibliográficos
Autores principales: Black, Markaisa, Milewski, David, Le, Tien, Ren, Xiaomeng, Xu, Yan, Kalinichenko, Vladimir V., Kalin, Tanya V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947867/
https://www.ncbi.nlm.nih.gov/pubmed/29642003
http://dx.doi.org/10.1016/j.celrep.2018.03.067