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FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts
Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant accumulation of collagen-secreting myofibroblasts. Development of effective therapies is limited due to incomplete understanding of molecular mechanisms regulating myofibroblast expansion. FOXF1 transcription factor is expressed in res...
Autores principales: | Black, Markaisa, Milewski, David, Le, Tien, Ren, Xiaomeng, Xu, Yan, Kalinichenko, Vladimir V., Kalin, Tanya V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947867/ https://www.ncbi.nlm.nih.gov/pubmed/29642003 http://dx.doi.org/10.1016/j.celrep.2018.03.067 |
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