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Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity

Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni is the most common. Pharmacological treatment is limited to the use of a single drug, praziquantel (P...

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Detalles Bibliográficos
Autores principales: Guimarães, Maria A., de Oliveira, Rosimeire N., de Almeida, Rebeca L., Mafud, Ana C., Sarkis, Ana L. V., Ganassin, Rayane, da Silva, Marcos P., Roquini, Daniel B., Veras, Leiz M., Sawada, Tânia C. H., Ropke, Cristina D., Muehlmann, Luis A., Joanitti, Graziella A., Kuckelhaus, Selma A. S., Allegretti, Silmara M., Mascarenhas, Yvonne P., de Moraes, Josué, Leite, José R. S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947907/
https://www.ncbi.nlm.nih.gov/pubmed/29750792
http://dx.doi.org/10.1371/journal.pone.0196667