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Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity
Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni is the most common. Pharmacological treatment is limited to the use of a single drug, praziquantel (P...
Autores principales: | Guimarães, Maria A., de Oliveira, Rosimeire N., de Almeida, Rebeca L., Mafud, Ana C., Sarkis, Ana L. V., Ganassin, Rayane, da Silva, Marcos P., Roquini, Daniel B., Veras, Leiz M., Sawada, Tânia C. H., Ropke, Cristina D., Muehlmann, Luis A., Joanitti, Graziella A., Kuckelhaus, Selma A. S., Allegretti, Silmara M., Mascarenhas, Yvonne P., de Moraes, Josué, Leite, José R. S. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947907/ https://www.ncbi.nlm.nih.gov/pubmed/29750792 http://dx.doi.org/10.1371/journal.pone.0196667 |
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