Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive

Major Depressive Disorder (MDD) is considered a “circuitopathy”, and brain stimulation therapies hold promise for ameliorating MDD symptoms, including hippocampal dysfunction. It is unknown if stimulation of upstream hippocampal circuitry, such as the entorhinal cortex (Ent), is antidepressive, alth...

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Detalles Bibliográficos
Autores principales: Yun, Sanghee, Reynolds, Ryan P., Petrof, Iraklis, White, Alicia, Rivera, Phillip D., Segev, Amir, Gibson, Adam D., Suarez, Maiko, Desalle, Matthew J., Ito, Naoki, Mukherjee, Shibani, Richardson, Devon R., Kang, Catherine E., Ahrens-Nicklas, Rebecca C., Soler, Ivan, Chetkovich, Dane M., Kourrich, Saïd, Coulter, Douglas A., Eisch, Amelia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948139/
https://www.ncbi.nlm.nih.gov/pubmed/29662202
http://dx.doi.org/10.1038/s41591-018-0002-1

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