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Transcript-indexed ATAC-seq for precision immune profiling

T cells create vast amounts of diversity in their T cell receptor (TCR) genes, enabling individual clones to recognize specific peptide-MHC ligands. Here we combine TCR sequencing and assay for transposase-accessible chromatin analysis at the single-cell level to provide information on the TCR speci...

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Detalles Bibliográficos
Autores principales:	Satpathy, Ansuman T., Saligrama, Naresha, Buenrostro, Jason D., Wei, Yuning, Wu, Beijing, Rubin, Adam J., Granja, Jeffrey M., Lareau, Caleb A., Li, Rui, Qi, Yanyan, Parker, Kevin R., Mumbach, Maxwell R., Serratelli, William S., Gennert, David G., Schep, Alicia N., Corces, M. Ryan, Khodadoust, Michael S., Kim, Youn H., Khavari, Paul A., Greenleaf, William J., Davis, Mark M., Chang, Howard Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948148/ https://www.ncbi.nlm.nih.gov/pubmed/29686426 http://dx.doi.org/10.1038/s41591-018-0008-8

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