Palmitic acid, but not high-glucose, induced myocardial apoptosis is alleviated by N‑acetylcysteine due to attenuated mitochondrial-derived ROS accumulation-induced endoplasmic reticulum stress

Pharmacological inhibition of reactive oxygen species (ROS) is a potential strategy to prevent diabetes-induced cardiac dysfunction. This study was designed to investigate precise effects of antioxidant N‑acetylcysteine (NAC) in alleviating diabetic cardiomyopathy (DCM). Echocardiography and histolo...

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Detalles Bibliográficos
Autores principales: He, Yang, Zhou, Lingyun, Fan, Zhiqiang, Liu, Shikun, Fang, Weijin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948205/
https://www.ncbi.nlm.nih.gov/pubmed/29752433
http://dx.doi.org/10.1038/s41419-018-0593-y

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