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DDB2 represses ovarian cancer cell dedifferentiation by suppressing ALDH1A1

Cancer stem cells (CSCs), representing the root of many solid tumors including ovarian cancer, have been implicated in disease recurrence, metastasis, and therapeutic resistance. Our previous study has demonstrated that the CSC subpopulation in ovarian cancer can be limited by DNA damage-binding pro...

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Detalles Bibliográficos
Autores principales: Cui, Tiantian, Srivastava, Amit Kumar, Han, Chunhua, Wu, Dayong, Wani, Nissar, Liu, Lu, Gao, Zhiqin, Qu, Meihua, Zou, Ning, Zhang, Xiaoli, Yi, Ping, Yu, Jianhua, Bell, Erica H., Yang, Shyh-Ming, Maloney, David J., Zheng, Yanfang, Wani, Altaf A., Wang, Qi-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948213/
https://www.ncbi.nlm.nih.gov/pubmed/29752431
http://dx.doi.org/10.1038/s41419-018-0585-y