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FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness

Therapy-induced expansion of cancer stem cells (CSCs) has been identified as one of the most critical factors contributing to therapeutic resistance, but the mechanisms of this adaptation are not fully understood. UHRF1 is a key epigenetic regulator responsible for therapeutic resistance, and contro...

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Detalles Bibliográficos
Autores principales: Yuan, Bowen, Liu, Youhong, Yu, Xiaohui, Yin, Linglong, Peng, Yuchong, Gao, Yingxue, Zhu, Qianling, Cao, Tuoyu, Yang, Yinke, Fan, Xuegong, Li, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948215/
https://www.ncbi.nlm.nih.gov/pubmed/29752436
http://dx.doi.org/10.1038/s41419-018-0631-9