Cargando…
FOXM1 contributes to taxane resistance by regulating UHRF1-controlled cancer cell stemness
Therapy-induced expansion of cancer stem cells (CSCs) has been identified as one of the most critical factors contributing to therapeutic resistance, but the mechanisms of this adaptation are not fully understood. UHRF1 is a key epigenetic regulator responsible for therapeutic resistance, and contro...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948215/ https://www.ncbi.nlm.nih.gov/pubmed/29752436 http://dx.doi.org/10.1038/s41419-018-0631-9 |