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Pigment epithelium-derived factor hinders photoreceptor cell death by reducing intracellular calcium in the degenerating retina

Calcium ions play a critical role in neuronal cell death. Pigment epithelium-derived factor (PEDF) is a promising neuroprotective protein for photoreceptor cells but the mechanisms mediating its effects against retinal degeneration are still not well characterized. We addressed this question in the...

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Detalles Bibliográficos
Autores principales:	Comitato, Antonella, Subramanian, Preeti, Turchiano, Giandomenico, Montanari, Monica, Becerra, S. Patricia, Marigo, Valeria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948223/ https://www.ncbi.nlm.nih.gov/pubmed/29752430 http://dx.doi.org/10.1038/s41419-018-0613-y

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