A Non-integrating Lentiviral Approach Overcomes Cas9-Induced Immune Rejection to Establish an Immunocompetent Metastatic Renal Cancer Model

The CRISPR-based technology has revolutionized genome editing in recent years. This technique allows for gene knockout and evaluation of function in cell lines in a manner that is far easier and more accessible than anything previously available. Unfortunately, the ability to extend these studies to...

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Detalles Bibliográficos
Autores principales: Hu, Junhui, Schokrpur, Shiruyeh, Archang, Maani, Hermann, Kip, Sharrow, Allison C., Khanna, Prateek, Novak, Jesse, Signoretti, Sabina, Bhatt, Rupal S., Knudsen, Beatrice S., Xu, Hua, Wu, Lily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948229/
https://www.ncbi.nlm.nih.gov/pubmed/29766028
http://dx.doi.org/10.1016/j.omtm.2018.02.009

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