Seizure-Suppressant and Neuroprotective Effects of Encapsulated BDNF-Producing Cells in a Rat Model of Temporal Lobe Epilepsy

Brain-derived neurotrophic factor (BDNF) may represent a therapeutic for chronic epilepsy, but evaluating its potential is complicated by difficulties in its delivery to the brain. Here, we describe the effects on epileptic seizures of encapsulated cell biodelivery (ECB) devices filled with genetica...

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Detalles Bibliográficos
Autores principales: Falcicchia, Chiara, Paolone, Giovanna, Emerich, Dwaine F., Lovisari, Francesca, Bell, William J., Fradet, Tracie, Wahlberg, Lars U., Simonato, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948312/
https://www.ncbi.nlm.nih.gov/pubmed/29766029
http://dx.doi.org/10.1016/j.omtm.2018.03.001

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