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Efficacy and Safety of Glycosidic Enzymes for Improved Gene Delivery to the Retina following Intravitreal Injection in Mice
Viral gene delivery is showing great promise for treating retinal disease. Although subretinal vector delivery has mainly been used to date, intravitreal delivery has potential advantages if low retinal transduction efficiency can be overcome. To this end, we investigated the effects of co-injection...
Autores principales: | Cehajic-Kapetanovic, Jasmina, Milosavljevic, Nina, Bedford, Robert A., Lucas, Robert J., Bishop, Paul N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948313/ https://www.ncbi.nlm.nih.gov/pubmed/29766027 http://dx.doi.org/10.1016/j.omtm.2017.12.002 |
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