Metastatic Gastric Signet Ring Cell Carcinoma Mimicking Crohn's Disease

Signet-ring cell carcinoma (SRCC) is an adenocarcinoma characterized by mucin-producing cells and most commonly arises in the stomach. Colonic SRCC can share features of colitis, including long segments of concentric bowel wall thickening and ulcerated mucosa with regions of sparing. We describe a r...

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Detalles Bibliográficos
Autores principales: Winter, Michael W., Dokmak, Amr, Marnoy, Zachary, Sinagare, Shweta, Levy, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5948315/
https://www.ncbi.nlm.nih.gov/pubmed/29774226
http://dx.doi.org/10.14309/crj.2018.36
Descripción
Sumario:Signet-ring cell carcinoma (SRCC) is an adenocarcinoma characterized by mucin-producing cells and most commonly arises in the stomach. Colonic SRCC can share features of colitis, including long segments of concentric bowel wall thickening and ulcerated mucosa with regions of sparing. We describe a rare case of metastatic gastric SRCC mimicking Crohn’s disease. Our patient underwent 2 colonoscopies, and biopsies revealed chronic active inflammation with no evidence of malignancy. The diagnosis of SRCC was only made after colectomy was performed for recurrent bowel obstruction.

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